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Bibframe Work

Title
Epigenetics and complex traits Epigenetics and complex traits
Type
Text
Subject
Epigenetics.
Epigenomics.
Language
English
Illustrative Content
illustrations
Classification
LCC: QH450 .E6557 2013 (Source: dlc)
2013 K-542 (Source: dnlm)
QU 460 (Source: dnlm)
Identified By
Lccn: 2013946543
Content
text (Source: rdacontent)
Summary
"Epigenetics and Complex Traits provides an overview of basic epigenetic phenomena that influence transmission of genetic traits, including the pivotal roles of epigenetic factors in genome integrity, genetic transmission and phenotypic variation at critical developmental points, interactions between epigenetic marks and genetic variation, as well as a detailed examination of how epigenetic considerations can alter interpretation and analysis of risks for complex traits. Included in this book are several overviews of the impact of inter-individual variation in epigenetic states, from major changes that cause congenital developmental defects to subtle changes and their impact on complex traits. In addition, there are chapters examining the relationship between epigenetic changes and genetic changes in human disease, methods for statistical analysis of epigenetics effects in human disease genetic studies or in population genetics, and a consideration of how epigenetics influences inheritance and analysis of inheritance. Epigenetics and Complex Traits is a resource for those who are working in mammalian genetics or analysis of human genetic data and are interested in the impact of epigenetics on inheritance."-- Back cover.
Table Of Contents
Part I: Epigenetic Phenomena in the Germ Line and Early Embryonic Development and Their Effects on the Inheritance of Genetic Traits
Epigenetic Reprogramming in the Mammalian Germline / Stéphanie Maupetit-Méhouas, David Nury, Philippe Arnaud
Establishment of Tissue-Specific Epigenetic States During Development / Ionel Sandovici
X-Chromosome Inactivation / Wendy P. Robinson ... [et al.]
Cis- and Trans-Effects Underlying Polar Overdominance at the Callipyge Locus / Michel Georges ... [et al.]
Transgenerational Epigenetic Effects and Complex Inheritance Patterns / Anna K. Naumova
Autosomal Monoallelic Expression / Virginia Savova, Alexander A. Gimelbrant
Part II: Epigenetic Variation in Health and Disease. Recurrent CNVs in the Etiology of Epigenetic Neurodevelopmental Disorders / Janine M. LaSalle, Mohammad Saharul Islam
Impact of the Early-Life Environment on the Epigenome and Behavioral Development / Benoit Labonté, Gustavo Turecki
Interaction Between Genetics and Epigenetics in Cancer / Amanda Ewart Toland
Part III: Impact of Epigenetics on Complex Trait Genetics and Analysis. Epigenetic Variation, Phenotypic Heritability, and Evolution / Robert E. Furrow, Freddy B. Christiansen, Marcus W. Feldman
Statistical Approaches for Detecting Transgenerational Genetic Effects in Humans / Janet S. Sinsheimer, Michelle M. Creek
Transmission Ratio Distortion: A Neglected Phenomenon with Many Consequences in Genetic Analysis and Population Genetics / Aurélie Labbe, Lam Opal Huang, Claire Infante-Rivard
Epigenome-Wide Association Studies: Potential Insights into Human Disease / Christopher G. Bell
Analytical Considerations for Epigenome-Wide Association Scans of Complex Traits / Jordana T. Bell.
Authorized Access Point
Naumova, Anna K., Epigenetics and complex traits
Authorized Access Point Variant
Greenwood, Celia M. T., Epigenetics and complex traits