Methyl-CpG-binding protein 2
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found: Work cat.: Qadri, L.H. Epigenetic regulation of hippocampus dependent learning, 2013:abstr. (This work examines the role of epigenetic mechanisms, specifically DNA methylation, in spatial learning using the Morris water maze (MWM), as well as the role of MeCP2, a protein that binds methylated DNA and regulates transcriptional activity, during memory consolidation following contextual fear conditioning)
found: MeSH browser, Sept. 30, 2013(Methyl-CpG-binding protein 2 -- A DNA-binding protein that interacts with methylated CpG islands. It plays a role in repressing genetic transcription and is frequently mutated in Rett syndrome. [MeSH UF] : MeCP2 protein)
found: OMIN (Online Mendelian Inheritance in Man) WWW home page, Sept. 30, 2013(Methyl-CpG-binding protein 2 -- MECP2, which binds methylated CpGs, is a chromatin-associated protein that can both activate and repress transcription. It is required for maturation of neurons and is developmentally regulated ... . Mutations in MECP2 can cause Rett syndrome, mental retardation, or encephalopathy, and have been implicated in autism susceptibility)
found: Lackie, J.M. A dictionary of biomedicine, 2010(methyl-CpG-binding protein 2 -- A protein (MeCP2, 486 aa) that binds to methylated CpG-rich regions of DNA and that contributes to silencing ... . MeCP2 regulates gene expression in neurons and is important in neurogenesis. The X-linked gene is mutated in Rett's syndrome and some cases of Angelman's syndrome)
found: European journal of biochemistry, Aug. 2003:p. 3263 (Methyl-CpG-binding protein 2 (MeCP2) is a multifunctional protein involved in chromatin organization and silencing of methylated DNA. ... MeCP2 is expressed in all tissues of the human body and, at particularly high levels, in neurons of the postnatal brain. This observation is in line with the fact that mutations in the MECP2 gene cause Rett syndrome)
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2013-09-16: new
2014-01-16: revised
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