found: Work cat: Dislocation and degradation of proteins from the endoplasmic reticulum, 2005:pref. (The present volume of Current Topics in Microbiology and Immunology contains seven chapters that illuminate various aspects of a protein's genesis and terminal fate in the endoplasmic reticulum (ER). ... It is therefore fitting that a special volume be devoted to the interplay between pathways of protein degradation in the ER and a wide variety of pathogens)
found: Hawley's condensed chemical dictionary, 1997(proteolysis -- The structural breakdown of proteins, usually by hydrolysis, as a result of the action of an enzyme, e.g., trypsin, pepsin, papain, etc.)
found: Chambers dictionary of science and technology, 1999(proteolysis -- The degradation of proteins into peptides and amino acids by cleavage of their peptide bonds)
found: MeSH browser, Mar. 27, 2015(Proteolysis -- Cleavage of proteins into smaller peptides or amino acids either by proteases or non-enzymatically (e.g., Hydrolysis). It does not include Protein processing, Post-translational) ([MeSH 450s]: Protein degradation; Protein digestion)
found: Encyclopedia Britannica, via WWW, Mar. 27, 2015articles by category/chemistry (proteolysis -- Process in which a protein is broken down partially, into peptides, or completely, into amino acids, by proteolytic enzymes, present in bacteria and in plants but most abundant in animals. Proteins in food are attacked in the stomach by pepsin and in the small intestine mainly by trypsin and chymotrypsin from the pancreas. Proteolytic enzymes are secreted as zymogens, which are themselves converted by proteolysis to their active forms. Many other zymogens or precursors undergo proteolysis to form active enzymes or proteins (e.g., fibrinogen to fibrin). In cells, proteolytic degradation of old proteins is part of cellular maintenance)
found: Journal of nutrition, June 2003:suppl. 2, p. 2052 (For the evaluation of the adequate intake of dietary amino acids and the assessment of their safety, basic knowledge of the protein metabolism in the body is essential. Protein synthesis and proteolysis are the major two fluxes. Both are coordinately regulated in the physiological state, but their mechanisms are entirely independent. The rate of proteolysis, as well as that of protein synthesis, is continually controlled to maintain homeostasis of body protein)
found: Biotechnology and bioengineering, Jan. 5, 2005:p. 102 (Causes of proteolytic degradation of secreted recombinant proteins produced in methylotrophic yeast Pichia pastoris ... A few remedial measures like addition of casamino acids, addition of protease inhibitors, or use of protease-deficient strains have been suggested as means to circumvent proteolytic degradation of the recombinant protein. ... However, no in-depth analysis on the conditions that promote proteolysis or the nature of the proteases acting on the desired protein is exactly known)
